Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 12/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978336 | 0.88 | HDAC6 (0.44) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978152 | 0.87 | ALDH1A1 (0.47) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978387 | 0.86 | HDAC4 (0.50) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978028 | 0.85 | HDAC4 (0.47) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978909 | 0.82 | HDAC4 (0.48) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978177 | 0.82 | MEN1 (0.41) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29977989 | 0.82 | HDAC4 (0.41) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29977967 | 0.81 | HDAC4 (0.50) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978582 | 0.81 | HDAC4 (0.50) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978914 | 0.81 | HDAC4 (0.50) | HDAC4HDAC6HDAC8HDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |