SCHEMBL29978240

SCHEMBL29978240

[N-]=[N+]=N[C@]1(n2ccc(N)nc2=O)C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLG P54098 2/20 0.47
P2RY2 P41231 10/20 0.44
P2RY6 Q15077 6/20 0.44
P2RY4 P51582 5/20 0.44
POLB P06746 1/20 0.44
POLRMT O00411 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6141746 0.84 POLG (0.51) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL17215886 0.84 POLG (0.51) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL25396644 0.84 POLG (0.51) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL585724 0.84 POLG (0.51) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL18797120 0.83 P2RY6 (0.55) P2RY2P2RY6P2RY4
SCHEMBL6038233 0.83 POLG (0.50) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL22577336 0.82 PDE3A (0.42) POLB
SCHEMBL597307 0.81 POLG (0.49) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL10900419 0.81 POLG (0.49) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL27451032 0.81 POLG (0.49) POLGP2RY2P2RY6P2RY4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622661-A1 CODON-OPTIMIZED OLIGONUCLEOTIDE FOR INDUCTION OF ELASTIN DE-NOVO SYNTHESIS IN MAMMALS Eberhard Karls Universität Tübingen, Medizinische Fakultät (DE) 2025-10-01 EP disclosed
CN-120202025-A Compositions for enhancing nucleic acid delivery 深圳鸿生生物科技有限公司 2025-06-24 CN disclosed
CN-112638362-B Dry powder formulations of messenger RNA 川斯勒佰尔公司 2025-06-13 CN disclosed
CN-119451988-B Anti-B7-H3 antibodies and uses thereof 乐普创一生物科技(上海)有限公司 2025-06-03 CN disclosed
CN-119930823-A Anti-CCR 8 antibodies and uses thereof 乐普创一生物科技(上海)有限公司 2025-05-06 CN disclosed
CN-119735678-A Tumor antigen dependent CD40 agonist single domain antibodies 乐普创一生物科技(上海)有限公司 2025-04-01 CN disclosed
CN-119662655-A Application of RNA molecule and composition thereof in tumor immunotherapy 武汉厚先生物医药有限公司 2025-03-21 CN disclosed
CN-119462954-A 5T4/CD40 bispecific antibodies 乐普创一生物科技(上海)有限公司 2025-02-18 CN disclosed
CN-119451988-A Anti-B7-H3 antibodies and uses thereof 乐普创一生物科技(上海)有限公司 2025-02-14 CN disclosed
CN-119110732-A Gene editing for improving joint function 奥泽生物疗法公司 2024-12-10 CN disclosed
CN-116059170-A Stereochemically enriched compositions for delivery of nucleic acids 川斯勒佰尔公司 2023-05-05 CN disclosed
CN-115916158-A Lipid nanoparticle formulations for mRNA delivery 翻译生物公司 2023-04-04 CN disclosed
CN-115515559-A Rectal delivery of messenger RNA 翻译生物公司 2022-12-23 CN disclosed
CN-115461042-A Improved method for preparing MRNA-loaded lipid nanoparticles 翻译生物公司 2022-12-09 CN disclosed
CN-115443338-A Methods and compositions for messenger RNA purification 翻译生物公司 2022-12-06 CN disclosed
CN-115427021-A Improved method for preparing MRNA-loaded lipid nanoparticles 翻译生物公司 2022-12-02 CN disclosed
CN-106795142-B Stereochemically enriched compositions for delivery of nucleic acids 川斯勒佰尔公司 2022-11-04 CN disclosed
US-11479768-B2 ATP-binding cassette family coding polyribonucleotides and formulations thereof ETHRIS GMBH (DE) 2022-10-25 US disclosed
CN-115244061-A Reagents and their use for modular enantioselective synthesis of C-P bonds 百时美施贵宝公司 2022-10-25 CN disclosed
CN-109072223-B Multimeric coding nucleic acids and uses thereof 川斯勒佰尔公司 2022-10-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11479768-B2 ATP-binding cassette family coding polyribonucleotides and formulations thereof ABCD3, ABCC3, ABCF1 POLG 319/4885P2RY2 1514/4885P2RY6 1123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.