SCHEMBL6038233

SCHEMBL6038233

Nc1ccn([C@@]2(CO)C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)n1

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
POLG P54098 2/20 0.50
POLB P06746 1/20 0.46
P2RY2 P41231 11/20 0.46
P2RY4 P51582 7/20 0.46
P2RY6 Q15077 6/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10900419 0.91 POLG (0.49) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL9328022 0.91 POLB (0.46) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL5708922 0.91 POLG (0.48) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL6141746 0.87 POLG (0.51) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL25396644 0.86 POLG (0.51) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL17215886 0.86 POLG (0.51) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL585724 0.86 POLG (0.51) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL597307 0.84 POLG (0.49) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL27451032 0.84 POLG (0.49) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL29978240 0.83 POLG (0.47) POLGPOLBP2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060270005-A1 Genomic library of cyanophage s-2l and functional analysis INSTITUT PASTEUR (FR) 2006-11-30 US disclosed