Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.55 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043578 | 1.00 | MCOLN3 (0.57) | MCOLN3PKML3MBTL1TSHRMCOLN2 | |
| SCHEMBL29978797 | 0.89 | TSHR (0.57) | MCOLN3PKML3MBTL1TSHRMCOLN2 | |
| SCHEMBL23043582 | 0.89 | TSHR (0.57) | MCOLN3PKML3MBTL1TSHRMCOLN2 | |
| SCHEMBL29978755 | 0.88 | MCOLN3 (0.74) | MCOLN3PKML3MBTL1MCOLN2MCOLN1 | |
| SCHEMBL23043740 | 0.88 | MCOLN3 (0.74) | MCOLN3PKML3MBTL1MCOLN2MCOLN1 | |
| SCHEMBL14355853 | 0.86 | MCOLN3 (0.71) | MCOLN3PKML3MBTL1TSHRMCOLN2 | |
| SCHEMBL23043569 | 0.85 | ALDH1A1 (0.61) | MCOLN3PKML3MBTL1MCOLN2MCOLN1 | |
| SCHEMBL23043627 | 0.85 | TSHR (0.60) | MCOLN3PKML3MBTL1TSHRMCOLN2 | |
| SCHEMBL29979719 | 0.85 | TSHR (0.60) | MCOLN3PKML3MBTL1TSHRMCOLN2 | |
| SCHEMBL23057205 | 0.81 | TSHR (0.57) | MCOLN3PKML3MBTL1TSHRMCOLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | MCOLN3 3/4885PKM 3754/4885L3MBTL1 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.