Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978389 | 0.93 | NAMPT (0.46) | MAPTNPSR1NAMPTHDAC4HDAC6 | |
| SCHEMBL29978083 | 0.93 | NPC1 (0.47) | MEN1KMT2AGAALMNAHTT | |
| SCHEMBL29979015 | 0.93 | MEN1 (0.47) | MEN1KMT2AGAALMNAHTT | |
| SCHEMBL29978109 | 0.92 | RAB9A (0.46) | ALDH1A1MAPTSMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL29978205 | 0.92 | HDAC4 (0.47) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL29977881 | 0.92 | MAPT (0.39) | MEN1KMT2AGAALMNAHTT | |
| SCHEMBL29978258 | 0.91 | NPC1 (0.52) | MEN1KMT2AGAALMNAHTT | |
| SCHEMBL29978900 | 0.90 | NPC1 (0.48) | GAALMNATSHRALDH1A1MAPT | |
| SCHEMBL29978312 | 0.88 | HDAC6 (0.39) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL29978914 | 0.87 | HDAC4 (0.50) | LMNAHTTTSHRHDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |