Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 17/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978301 | 0.93 | HDAC4 (0.52) | HDAC4HDAC6HDAC8HDAC2PLA2G1B | |
| SCHEMBL29978476 | 0.91 | HDAC4 (0.50) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978604 | 0.91 | HDAC4 (0.50) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29977911 | 0.91 | HDAC4 (0.44) | HDAC4HDAC6HDAC8HDAC2PLA2G1B | |
| SCHEMBL29978650 | 0.90 | HDAC4 (0.48) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978213 | 0.90 | HDAC4 (0.50) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978646 | 0.90 | HDAC4 (0.48) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978179 | 0.90 | HDAC4 (0.49) | HDAC4HDAC6HDAC8HDAC2MAPT | |
| SCHEMBL29977830 | 0.88 | HDAC4 (0.47) | HDAC4HDAC6HDAC8HDAC2MGLL | |
| SCHEMBL29978688 | 0.87 | RAB9A (0.46) | HDAC4HDAC6HDAC8HDAC2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |