Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978177 | 0.93 | MEN1 (0.41) | MEN1KMT2AHDAC6HDAC4HDAC8 | |
| SCHEMBL29978728 | 0.90 | HDAC6 (0.44) | MEN1KMT2AHDAC6HDAC4HDAC8 | |
| SCHEMBL29978604 | 0.89 | HDAC4 (0.50) | HDAC6HDAC4HDAC8HDAC2HDAC1 | |
| SCHEMBL29977903 | 0.85 | TAS1R3 (0.43) | MEN1KMT2AHDAC6HDAC4HDAC8 | |
| SCHEMBL29977911 | 0.85 | HDAC4 (0.44) | HDAC6HDAC4HDAC8HDAC2HDAC1 | |
| SCHEMBL29978949 | 0.85 | HDAC4 (0.41) | HDAC6HDAC4HDAC8HDAC2HDAC1 | |
| SCHEMBL29978213 | 0.84 | HDAC4 (0.50) | HDAC6HDAC4HDAC8HDAC2HDAC1 | |
| SCHEMBL29978646 | 0.84 | HDAC4 (0.48) | MEN1KMT2AHDAC6HDAC4HDAC8 | |
| SCHEMBL29978650 | 0.84 | HDAC4 (0.48) | MEN1KMT2AHDAC6HDAC4HDAC8 | |
| SCHEMBL29977922 | 0.84 | ALDH1A1 (0.47) | HDAC6HDAC4HDAC8HDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |