Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21972975 | 1.00 | ALDH1A1 (0.64) | ALDH1A1CYP2C9CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL31411536 | 0.91 | GSK3B (0.56) | ALDH1A1CYP2C9CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL21905603 | 0.88 | POLB (0.53) | ALDH1A1CYP2C9CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL21972352 | 0.87 | TP53 (0.68) | ALDH1A1CYP2C9CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL23768992 | 0.87 | ALDH1A1 (0.71) | ALDH1A1CYP2C9CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL29978848 | 0.87 | ALDH1A1 (0.71) | ALDH1A1CYP2C9CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL31411740 | 0.85 | POLB (0.58) | ALDH1A1CYP2C9CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL8551997 | 0.84 | POLB (0.70) | ALDH1A1POLBSMN1; SMN2MAPTLMNA | |
| SCHEMBL31411545 | 0.84 | POLB (0.60) | ALDH1A1CYP2C9CYP2C19POLBSMN1; SMN2 | |
| SCHEMBL21972974 | 0.83 | MAPT (0.78) | ALDH1A1CYP2C9CYP2C19POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151304-B | Small molecule interferon gene stimulating factor (STING) antagonists | 库拉德夫制药私人有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |
| EP-4384267-A1 | SMALL MOLECULE STING ANTAGONISTS | Curadev Pharma Pvt. Ltd. (IN) | 2024-06-19 | — | — | EP | disclosed |
| EP-4384268-A1 | SMALL MOLECULE UREA DERIVATIVES AS STING ANTAGONISTS | Curadev Pharma Pvt. Ltd. (IN) | 2024-06-19 | — | — | EP | disclosed |
| CN-118159535-A | Small molecule STING antagonists | 库拉德夫制药私人有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118019738-A | Small molecule urea derivatives as STING antagonists | 库拉德夫制药私人有限公司 | 2024-05-10 | — | — | CN | disclosed |
| WO-2023017452-A1 | SMALL MOLECULE UREA DERIVATIVES AS STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023017451-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |
| CN-115151304-A | Small molecule interferon gene stimulating factor (STING) antagonists | 库拉德夫制药私人有限公司 | 2022-10-04 | — | — | CN | disclosed |