Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411699 | 0.85 | POLB (0.65) | POLBSMN1; SMN2ALDH1A1L3MBTL1USP2 | |
| SCHEMBL29978554 | 0.84 | ALDH1A1 (0.64) | POLBSMN1; SMN2ALDH1A1NPSR1LMNA | |
| SCHEMBL21972975 | 0.84 | ALDH1A1 (0.64) | POLBSMN1; SMN2ALDH1A1NPSR1LMNA | |
| SCHEMBL25920688 | 0.84 | ALDH1A1 (0.65) | POLBSMN1; SMN2ALDH1A1L3MBTL1USP2 | |
| SCHEMBL5422370 | 0.83 | POLB (1.00) | POLBSMN1; SMN2ALDH1A1L3MBTL1USP2 | |
| SCHEMBL31411545 | 0.82 | POLB (0.60) | POLBSMN1; SMN2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL31411654 | 0.81 | ALDH1A1 (0.63) | POLBSMN1; SMN2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL21972352 | 0.81 | TP53 (0.68) | POLBSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL31411768 | 0.81 | POLB (0.61) | POLBSMN1; SMN2ALDH1A1L3MBTL1USP2 | |
| SCHEMBL31411740 | 0.81 | POLB (0.58) | POLBSMN1; SMN2ALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846112-A1 | BICYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997008164-A1 | BICYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-06 | — | — | WO | disclosed |