Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28341354 | 1.00 | MAPT (0.70) | MAPTPOLBGAARECQLTSHR | |
| SCHEMBL28880754 | 0.83 | MAPT (0.66) | MAPTPOLBGAARECQLTSHR | |
| SCHEMBL29978938 | 0.80 | MAPT (0.46) | MAPTPOLBGAARECQLTSHR | |
| SCHEMBL28344388 | 0.80 | MAPT (0.46) | MAPTPOLBGAARECQLTSHR | |
| SCHEMBL3819641 | 0.78 | HPGD (0.60) | MAPTPOLBGAARECQLKDM4E | |
| SCHEMBL30451351 | 0.75 | RAB9A (0.73) | MAPTPOLBGAARECQLCYP2C19 | |
| SCHEMBL733872 | 0.74 | CYP2C19 (0.58) | MAPTPOLBGAARECQLTSHR | |
| SCHEMBL1307557 | 0.74 | TP53 (0.67) | MAPTPOLBGAARECQLTSHR | |
| SCHEMBL1624948 | 0.74 | MAPT (0.55) | MAPTPOLBGAARECQLTSHR | |
| SCHEMBL3715383 | 0.74 | HTT (0.51) | MAPTPOLBGAARECQLTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494431-B | Azacyclo derivative, preparation method and medical application thereof | 苏州浦合医药科技有限公司 | 2022-11-04 | — | — | CN | disclosed |