Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN2 | Q8IZK6 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979662 | 1.00 | MCOLN2 (0.52) | MCOLN2L3MBTL1PKMMCOLN3ALDH1A1 | |
| SCHEMBL23057141 | 0.90 | GAA (0.45) | MCOLN2L3MBTL1PKMMCOLN3ALDH1A1 | |
| SCHEMBL29978499 | 0.86 | MCOLN2 (0.44) | MCOLN2PKMALDH1A1KDM4ELMNA | |
| SCHEMBL23057173 | 0.86 | MCOLN2 (0.44) | MCOLN2PKMALDH1A1KDM4ELMNA | |
| SCHEMBL23057135 | 0.86 | MCOLN2 (0.46) | MCOLN2L3MBTL1PKMMCOLN3ALDH1A1 | |
| SCHEMBL23057264 | 0.85 | ALDH1A1 (0.49) | MCOLN2L3MBTL1PKMMCOLN3ALDH1A1 | |
| SCHEMBL29978490 | 0.85 | ALDH1A1 (0.49) | MCOLN2L3MBTL1PKMMCOLN3ALDH1A1 | |
| SCHEMBL29512769 | 0.84 | ALDH1A1 (0.47) | MCOLN2L3MBTL1PKMMCOLN3ALDH1A1 | |
| SCHEMBL23057180 | 0.82 | MCOLN3 (0.68) | MCOLN2L3MBTL1PKMMCOLN3ALDH1A1 | |
| SCHEMBL23043738 | 0.81 | MCOLN3 (0.70) | MCOLN2L3MBTL1PKMMCOLN3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | MCOLN2 2/4885L3MBTL1 794/4885PKM 3754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.