Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 2/20 | 0.46 |
| ▸ | EDNRA | P25101 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29085871 | 1.00 | KDM4E (0.60) | KDM4EPKMMEN1KMT2AHSD11B1 | |
| SCHEMBL6454935 | 0.84 | KDM4E (0.74) | KDM4EPKMMEN1KMT2AHSD11B1 | |
| SCHEMBL27493659 | 0.84 | KDM4E (0.77) | KDM4EPKMHSD11B1ALDH1A1HPGD | |
| SCHEMBL22485019 | 0.82 | KDM4E (0.55) | KDM4EPKMMEN1KMT2AHSD11B1 | |
| SCHEMBL20047235 | 0.79 | PGR (0.58) | KDM4EPKMMEN1KMT2APGR | |
| SCHEMBL28551236 | 0.77 | HSD11B1 (0.53) | KDM4EPKMMEN1KMT2AHSD11B1 | |
| SCHEMBL3485583 | 0.75 | KDM4E (1.00) | KDM4EPKMMEN1KMT2AHSD11B1 | |
| SCHEMBL28007734 | 0.75 | KDM4E (0.74) | KDM4EPKMMEN1KMT2AHSD11B1 | |
| SCHEMBL1403074 | 0.72 | PGR (0.75) | PKMMEN1KMT2APGRBRD4 | |
| SCHEMBL30565215 | 0.72 | PGR (0.75) | PKMMEN1KMT2APGRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160222-B | Hydroxamic acid compound containing quinoline or isoquinoline and preparation and application thereof | 沈阳药科大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-115160222-A | Hydroxamic acid compound containing quinoline or isoquinoline and preparation and application thereof | 沈阳药科大学 | 2022-10-11 | — | — | CN | disclosed |