Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490092 | 0.86 | HDAC1 (0.34) | HTTLMNADRD2DRD3 | |
| SCHEMBL23769067 | 0.86 | HDAC1 (0.34) | HTTLMNADRD2DRD3 | |
| SCHEMBL31490100 | 0.82 | KMT2A (0.38) | ALDH1A1HTTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL23769065 | 0.82 | KMT2A (0.38) | ALDH1A1HTTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL29979358 | 0.74 | CCR3 (0.36) | HTTSMN1; SMN2 | |
| SCHEMBL23769066 | 0.74 | CCR3 (0.36) | HTTSMN1; SMN2 | |
| SCHEMBL11214418 | 0.73 | SMN1; SMN2 (0.50) | SIGMAR1HTR1AALDH1A1NPC1LMNA | |
| SCHEMBL11213584 | 0.72 | LMNA (0.56) | SIGMAR1HTR1AALDH1A1GAAHTT | |
| SCHEMBL30343043 | 0.70 | SIRT1 (0.53) | SIGMAR1HTR1AALDH1A1GAAHTT | |
| SCHEMBL23769085 | 0.68 | MEN1 (0.39) | SIGMAR1ALDH1A1GAALMNADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151304-A | Small molecule interferon gene stimulating factor (STING) antagonists | 库拉德夫制药私人有限公司 | 2022-10-04 | — | — | CN | disclosed |