SCHEMBL299791

SCHEMBL299791

C=CC(OC(=O)C(=C)C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.42
ELANE P08246 1/20 0.41
ALDH1A1 P00352 4/20 0.39
CYP3A4 P08684 3/20 0.39
HCAR2 Q8TDS4 1/20 0.38
LMNA P02545 4/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 2/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
CYP2D6 P10635 1/20 0.34
SRC P12931 1/20 0.34
KDM4E B2RXH2 4/20 0.34
MAPT P10636 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
USP2 O75604 2/20 0.33
TP53 P04637 2/20 0.33
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27082345 0.88 HPGD (0.43) HPGDALDH1A1CYP3A4HCAR2LMNA
SCHEMBL26936566 0.85 HPGD (0.41) HPGDELANEALDH1A1CYP3A4HCAR2
SCHEMBL7778106 0.85 HPGD (0.37) HPGDELANEALDH1A1CYP3A4HCAR2
SCHEMBL61038 0.84 CYP3A4 (0.50) HPGDALDH1A1CYP3A4HCAR2LMNA
SCHEMBL4336062 0.83 HCAR2 (0.31) HPGDELANEHCAR2
SCHEMBL9682256 0.82 PTGS2 (0.40) HPGDELANECYP3A4CYP2C19CYP2D6
SCHEMBL27653587 0.82 TDP1 (0.41) HPGDALDH1A1CYP3A4HCAR2LMNA
SCHEMBL24667207 0.81 CYP1A2 (0.47) HPGDELANEALDH1A1CYP3A4HCAR2
SCHEMBL27713535 0.81 CYP1A2 (0.47) HPGDELANEALDH1A1CYP3A4HCAR2
SCHEMBL2886386 0.80 CYP2C19 (0.43) HPGDALDH1A1CYP3A4HCAR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3235852-A1 PHOTOACTIVE POLYMER MATERIALS Rolic AG (CH) 2017-10-25 EP claimed
EP-2655478-B1 PHOTOACTIVE POLYMER MATERIALS ROLIC AG (CH) 2017-06-14 EP claimed
CN-106833722-A A kind of lightweight desulfurating agent and preparation method thereof 刘望舒 2017-06-13 CN claimed
CN-104046777-A Method using tributyl phosphate resin for fractional extraction to separate zirconium and hafnium GEN RES INST NONFERROUS METALS 2014-09-17 CN claimed
CN-103819859-A High-foaming expendable casting material and preparation method thereof WUHAN INST TECHNOLOGY 2014-05-28 CN claimed
US-20130281564-A1 PHOTOACTIVE POLYMER MATERIALS ROLIC AG (CH) 2013-10-24 US claimed
CN-102112528-B Photochromic polymer and composition comprising photochromic polymer ADVANCED POLYMERIK PTY LTD 2013-08-28 CN claimed
CN-103214891-A Compound containing carbon nano-tube, hard coating and forming method thereof and hard coating film FORHOUSE PHOTOELECTRIC INDUSTRY SUZHOU CORP 2013-07-24 CN claimed
CN-101993602-B Highly thermally-conductive moldable thermoplastic composites and compositions LAIRD TECHNOLOGIES SHENZHEN LTD 2013-07-10 CN claimed
CN-101033393-B Photochromic compounds TRANSITIONS OPTICAL INC 2013-06-05 CN claimed
US-20020061996-A1 Photocrosslinkable polymers BUCHECKER RICHARD (CH) 2002-05-23 US claimed
US-6335409-B1 LIQUID CRYSTAL ORIENTATION ROLIC AG (CH) 2002-01-01 US claimed
EP-0763552-B1 Curable, photoactive polymeric materials ROLIC AG (CH) 2001-09-19 EP claimed
CN-1053445-C Photochromic naphthopyran compounds PPG INDUSTRIES INC (US) 2000-06-14 CN claimed
CN-1251116-A Photochromic polyurethane coating and articles having such coating PPG IND OHIO INC (US) 2000-04-19 CN claimed
CN-1226267-A Noval photochromic indeno-fused naphthopyrans OPTICAL TRANSFORMING CO (US) 1999-08-18 CN claimed
EP-0524557-B1 Ocular lens material MENICON CO LTD (JP) 1996-01-17 EP claimed
US-5250583-A Polymer of fluoroalkyl silicon-containing alkyl fumarate, N-vinyllactam, acrylic or methacrylic acid, crosslinkable monomer MENICON CO., LTD. (JP) 1993-10-05 US claimed
EP-0524557-A2 Ocular lens material Menicon Co., Ltd. (JP) 1993-01-27 EP claimed
US-4889894-A Compatible polymer mixtures ROHM GMBH (DE) 1989-12-26 US claimed