Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.30 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299791 | 0.82 | HPGD (0.42) | TP53TDP1HPGDCYP3A4CYP2D6 | |
| SCHEMBL3974976 | 0.74 | ALDH1A1 (0.52) | PTGS2TP53TDP1CYP3A4CYP2D6 | |
| Styrene SCHEMBL7927920 | 0.74 | ALDH1A1 (0.44) | PTGS2TDP1HPGDCYP3A4MAPT | |
| Styrene SCHEMBL27896138 | 0.74 | ALDH1A1 (0.44) | PTGS2TDP1HPGDCYP3A4MAPT | |
| Styrene SCHEMBL27602216 | 0.74 | ALDH1A1 (0.44) | PTGS2TDP1HPGDCYP3A4MAPT | |
| Styrene SCHEMBL28298815 | 0.72 | MEN1 (0.40) | PTGS2TDP1HPGDCYP3A4MAPT | |
| SCHEMBL7778106 | 0.72 | HPGD (0.37) | HPGDCYP3A4CYP2C19ELANE | |
| Styrene SCHEMBL11394471 | 0.72 | TSHR (0.45) | PTGS2TDP1HPGDCYP3A4MAPT | |
| SCHEMBL24667207 | 0.71 | CYP1A2 (0.47) | TDP1HPGDCYP3A4CYP2D6MAPT | |
| SCHEMBL27713535 | 0.71 | CYP1A2 (0.47) | TDP1HPGDCYP3A4CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169980-A | Catalytic reaction of benzyl chloride and alkali metal methacrylate | ELF ATOCHEM S.A. (FR) | 1992-12-08 | — | — | US | disclosed |