Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23057110 | 0.89 | ALDH1A1 (0.51) | MCOLN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL23057222 | 0.88 | ALDH1A1 (0.49) | MCOLN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL29978639 | 0.83 | ALDH1A1 (0.55) | MCOLN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL23057226 | 0.83 | ALDH1A1 (0.55) | MCOLN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL29978597 | 0.81 | ALDH1A1 (0.47) | MCOLN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL29978470 | 0.78 | GAA (0.48) | MCOLN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL23057220 | 0.77 | ALDH1A1 (0.53) | MCOLN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL29979661 | 0.76 | GAA (0.51) | MCOLN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL29979103 | 0.76 | MCOLN2 (0.46) | MCOLN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL23057021 | 0.74 | MCOLN2 (0.53) | MCOLN2ALDH1A1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | MCOLN2 2/4885ALDH1A1 1368/4885LMNA 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.