Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.66 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935266 | 1.00 | ACHE (0.66) | ACHEPBRM1CYP19A1ESR1MAOA | |
| SCHEMBL24483566 | 0.82 | PBRM1 (0.53) | ACHEPBRM1CYP19A1MAOB | |
| SCHEMBL6475805 | 0.81 | ACHE (0.66) | ACHEPBRM1 | |
| SCHEMBL29980313 | 0.81 | ACHE (0.66) | ACHEPBRM1 | |
| SCHEMBL2481939 | 0.79 | ACHE (1.00) | ACHEMAOAMAOB | |
| SCHEMBL29893908 | 0.79 | ACHE (1.00) | ACHEMAOAMAOB | |
| SCHEMBL8091521 | 0.79 | ACHE (0.69) | ACHEMAOA | |
| SCHEMBL8099829 | 0.79 | ACHE (0.69) | ACHEMAOA | |
| SCHEMBL2585275 | 0.78 | ACHE (1.00) | ACHE | |
| SCHEMBL30666550 | 0.78 | ACHE (0.66) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563438-B | Organic compounds | 奇华顿股份有限公司 | 2022-11-04 | — | — | CN | disclosed |