Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.66 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475805 | 1.00 | ACHE (0.66) | ACHEPBRM1TDP1L3MBTL1ADRA2A | |
| SCHEMBL1500072 | 0.85 | METAP1 (0.56) | ACHEPBRM1ADRA2APNMTADRA2B | |
| SCHEMBL22012874 | 0.85 | METAP1 (0.56) | ACHEPBRM1ADRA2APNMTADRA2B | |
| SCHEMBL447309 | 0.82 | TDP1 (0.47) | ACHEPBRM1TDP1L3MBTL1PARP1 | |
| SCHEMBL6935266 | 0.81 | ACHE (0.66) | ACHEPBRM1 | |
| SCHEMBL29979385 | 0.81 | ACHE (0.66) | ACHEPBRM1 | |
| SCHEMBL17675410 | 0.79 | METAP1 (0.44) | ACHEPBRM1TDP1L3MBTL1PARP1 | |
| SCHEMBL29893908 | 0.79 | ACHE (1.00) | ACHEPARP1PARP10METAP1HTR2A | |
| SCHEMBL2481939 | 0.79 | ACHE (1.00) | ACHEPARP1PARP10METAP1HTR2A | |
| SCHEMBL22039455 | 0.78 | PNMT (0.42) | ACHEPBRM1TDP1L3MBTL1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563438-B | Organic compounds | 奇华顿股份有限公司 | 2022-11-04 | — | — | CN | disclosed |