Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2151219 | 0.84 | SIGMAR1 (0.62) | SIGMAR1TAAR1MAOBHTR2AHTR3A | |
| SCHEMBL23159894 | 0.82 | ALOX15 (0.47) | SIGMAR1TAAR1MAOBHTR2AALDH1A1 | |
| SCHEMBL6004011 | 0.80 | SIGMAR1 (0.46) | SIGMAR1TAAR1MAOBHTR2AALDH1A1 | |
| SCHEMBL30929931 | 0.80 | SIGMAR1 (0.46) | SIGMAR1TAAR1MAOBHTR2AALDH1A1 | |
| SCHEMBL6159094 | 0.79 | MEN1 (0.43) | SIGMAR1TAAR1HTR2AALDH1A1ALOX15 | |
| SCHEMBL6365744 | 0.79 | SIGMAR1 (0.47) | SIGMAR1MAOBHTR2AALOX15 | |
| SCHEMBL2302649 | 0.78 | KMT2A (0.50) | TAAR1GPR84MAOBHTR2AALDH1A1 | |
| SCHEMBL2844470 | 0.78 | TAAR1 (0.47) | TAAR1GPR84ALDH1A1IGF1RALOX15 | |
| SCHEMBL10812127 | 0.78 | HTR2A (0.60) | SIGMAR1TAAR1GPR84MAOBHTR2A | |
| SCHEMBL23159850 | 0.77 | ALOX15 (0.47) | SIGMAR1TAAR1MAOBALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286575-A | Quinolinone seven-eight membered ring derivative and synthesis method and application thereof | 河南科技大学 | 2022-11-04 | — | — | CN | disclosed |