Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143209 | 1.00 | TSHR (0.46) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28271262 | 0.98 | TSHR (0.45) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL23829919 | 0.79 | ALDH1A1 (0.47) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL826630 | 0.78 | TSHR (0.50) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL30389430 | 0.78 | ALDH1A1 (0.46) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL28720537 | 0.77 | TSHR (0.48) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL3311690 | 0.75 | ALDH1A1 (0.48) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL1917858 | 0.75 | TSHR (0.46) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL2144876 | 0.75 | TSHR (0.50) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL7942312 | 0.75 | GAA (0.50) | TSHRLMNAALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4058016-A1 | THIOPHENE COMPOUNDS WITH CYCLIC AMIDES, AND USES THEREOF | Capulus Therapeutics, LLC (US) | 2022-09-21 | — | — | EP | disclosed |