Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979690 | 1.00 | TSHR (0.46) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28271262 | 0.98 | TSHR (0.45) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL23829919 | 0.79 | ALDH1A1 (0.47) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL826630 | 0.78 | TSHR (0.50) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL30389430 | 0.78 | ALDH1A1 (0.46) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL28720537 | 0.77 | TSHR (0.48) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL3311690 | 0.75 | ALDH1A1 (0.48) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL1917858 | 0.75 | TSHR (0.46) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL2144876 | 0.75 | TSHR (0.50) | TSHRLMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL7942312 | 0.75 | GAA (0.50) | TSHRLMNAALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106588915-B | The synthetic method of Alzheimer's disease Protein tau diagnosis and treatment one targeted drug precursor | 浙江大学 | 2018-12-04 | — | — | CN | claimed |
| CN-106588915-A | Synthesis method of diagnosis and treatment integrated target prodrug for AD (Alzheimer's disease) tau protein | 浙江大学 | 2017-04-26 | — | — | CN | claimed |
| CN-101221169-A | Homogeneous phase time discrimination fluorescence immunity analysis chelating agent and its preparing method | CHANGCHUN APPLIED CHEMISTRY (CN) | 2008-07-16 | — | — | CN | claimed |
| CN-115650982-B | Compounds for imaging TAU protein aggregates | AC免疫有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-121537340-A | 4,4' - (Perfluoropropane-2, 2-diyl) bis (2- ((4-aminopyridine-2-yl) amino) phenol), and preparation method and application thereof | 山东阳谷华泰化工股份有限公司 | 2026-02-17 | — | — | CN | disclosed |
| EP-4665331-A1 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| EP-4522618-A1 | TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS | Merck Patent GmbH (DE) | 2025-03-19 | — | — | EP | disclosed |
| EP-3604305-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | WAKUNAGA PHARMA CO LTD (JP) | 2024-08-28 | — | — | EP | disclosed |
| WO-2024173219-A1 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-08-22 | — | — | WO | disclosed |
| US-12053459-B2 | CDK2 inhibitors and methods of using the same | CEDILLA THERAPEUTICS, INC. (MA) | 2024-08-06 | — | — | US | disclosed |
| US-20240199603-A1 | HPK1 ANTAGONISTS AND USES THEREOF | SCHRÖDINGER, INC. | 2024-06-20 | — | — | US | disclosed |
| CN-1551876-A | 6-aryl-4-aminopicolinates and their use as herbicides | �ݶ�ũ������˾ | 2004-12-01 | — | — | CN | disclosed |
| CN-1148356-C | Benzosulfone derivatives | - | 2004-05-05 | — | — | CN | disclosed |
| US-6521643-B1 | Prevention and/or treatment of nitric oxide synthasey medi-ated diseases such as adult respiratory distress syndrome, myocarditis, synovitis, septic shock, diabetes, ulcerative colitis, cerebral infarction, osteoarthritis | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-02-18 | — | — | US | disclosed |
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |
| CN-1231287-A | Benzosulfone derivatives | HOFFMANN LA ROCHE (CH) | 1999-10-13 | — | — | CN | disclosed |
| EP-0711601-A2 | Catalyst for multistage etherification with high conversion of T-butanol | TEXACO DEVELOPMENT CORPORATION (US) | 1996-05-15 | — | — | EP | disclosed |
| US-5196422-A | Antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199603-A1 | HPK1 ANTAGONISTS AND USES THEREOF | PDXK, HIPK1, PCK1 | TSHR 4353/4885LMNA 3355/4885ALDH1A1 4740/4885 |
| US-12053459-B2 | CDK2 inhibitors and methods of using the same | CDK2, CDK20, CDK2AP2 | TSHR 3996/4885LMNA 1270/4885ALDH1A1 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.