Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29117187 | 1.00 | TSHR (0.44) | TSHRTNFRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL19857729 | 0.90 | TSHR (0.44) | TSHRTNFRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29979676 | 0.88 | TLR8 (0.40) | TSHRTNFRAB9ASMN1; SMN2KCNH2 | |
| SCHEMBL2655223 | 0.83 | SMN1; SMN2 (0.52) | TSHRTNFRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31667365 | 0.82 | KCNH2 (0.39) | RAB9AMEN1KMT2AKCNH2TLR8 | |
| SCHEMBL29980097 | 0.82 | CYP1A2 (0.41) | TSHRRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31667604 | 0.81 | MTNR1A (0.40) | TSHRRAB9ASMN1; SMN2KCNH2TLR8 | |
| SCHEMBL29117268 | 0.80 | IKBKB (0.38) | MEN1KMT2AKCNH2TLR8ACSS2 | |
| SCHEMBL637860 | 0.79 | BRD4 (0.39) | TNFRAB9ANPC1 | |
| SCHEMBL13273918 | 0.77 | ALDH1A1 (0.54) | TSHRTNFRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284365-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| CN-117177744-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022165513-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2022-08-04 | — | — | WO | disclosed |