SCHEMBL29979999

SCHEMBL29979999

CCOc1cccc(C(C)(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.55
TP53 P04637 1/20 0.55
SOD1 P00441 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.53
LMNA P02545 2/20 0.53
POLB P06746 1/20 0.53
HTT P42858 1/20 0.53
MAPK1 P28482 2/20 0.45
CYP2C19 P33261 2/20 0.45
CYP2C9 P11712 1/20 0.45
NQO1 P15559 1/20 0.44
LTA4H P09960 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
GRM2 Q14416 1/20 0.43
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5619009 1.00 CYP3A4 (0.55) CYP3A4TP53SOD1L3MBTL1LMNA
Alcohol SCHEMBL28543970 0.94 L3MBTL1 (0.51) CYP3A4TP53SOD1L3MBTL1LMNA
SCHEMBL28543971 0.88 CYP3A4 (0.49) CYP3A4TP53SOD1L3MBTL1LMNA
SCHEMBL10211503 0.85 L3MBTL1 (0.57) CYP3A4SOD1L3MBTL1LMNAPOLB
SCHEMBL13191971 0.85 TP53 (0.52) CYP3A4TP53SOD1L3MBTL1LMNA
SCHEMBL1546661 0.85 TP53 (0.52) CYP3A4TP53SOD1L3MBTL1LMNA
SCHEMBL12251342 0.83 L3MBTL1 (0.60) SOD1L3MBTL1LMNAPOLBHTT
SCHEMBL1547082 0.83 TP53 (0.50) CYP3A4TP53SOD1L3MBTL1LMNA
SCHEMBL13639099 0.83 L3MBTL1 (0.56) SOD1L3MBTL1LMNAPOLBHTT
SCHEMBL25005890 0.82 SOD1 (0.53) CYP3A4SOD1L3MBTL1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112624993-B Oxazoline derivative with nitrogen heterocyclic ring structure, preparation thereof and application thereof in preventing and controlling phytophagous mites 南开大学 2022-11-11 CN disclosed