Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997363 | 0.84 | SRD5A2 (0.63) | PTPN11GAARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4171948 | 0.83 | CYP2C8 (0.69) | PTPN11LMNAGAARAB9ASMN1; SMN2 | |
| SCHEMBL4961133 | 0.82 | PTPN1 (0.50) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2997357 | 0.81 | SMN1; SMN2 (0.56) | PTPN11RAB9ASMN1; SMN2MRGPRX4NPC1 | |
| SCHEMBL12663514 | 0.80 | AKR1C3 (0.51) | PTPN11LMNAGAAMRGPRX4FOLH1 | |
| SCHEMBL15266493 | 0.80 | THRA (0.53) | LMNAGAARAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL4602802 | 0.80 | HDAC4 (0.62) | LMNAGAARAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL26365859 | 0.79 | FOLH1 (0.62) | PTPN11LMNAGAARAB9ASMN1; SMN2 | |
| SCHEMBL4254012 | 0.79 | STIM1 (0.62) | LMNAGAARAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL14980440 | 0.78 | MTNR1A (0.47) | LMNAMTNR1AMTNR1BRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | SALTIGO GMBH (DE) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184977-A1 | Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines | MON2, ZRANB2, GRIA2 | PTPN11 2250/4885LMNA 3666/4885GAA 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.