Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.51 |
| ▸ | PRNP | P04156 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114821 | 1.00 | HPGD (0.58) | HPGDHTTRXFP1PRNPKDM4E | |
| SCHEMBL11775727 | 0.89 | HPGD (0.49) | HPGDHTTRXFP1PRNPKDM4E | |
| SCHEMBL6899659 | 0.87 | RXFP1 (0.53) | HPGDRXFP1PRNPKDM4ENPSR1 | |
| SCHEMBL8737022 | 0.85 | SMN1; SMN2 (0.63) | HPGDHTTRXFP1PRNPKDM4E | |
| SCHEMBL8565804 | 0.85 | HPGD (0.43) | HPGDHTTRXFP1PRNPKDM4E | |
| SCHEMBL3389504 | 0.85 | KDM1A (0.53) | HPGDHTTRXFP1PRNPKDM4E | |
| SCHEMBL31280487 | 0.85 | SMN1; SMN2 (0.63) | HPGDHTTRXFP1PRNPKDM4E | |
| SCHEMBL2098479 | 0.82 | RXFP1 (0.53) | HPGDRXFP1PRNPKDM4ENPSR1 | |
| SCHEMBL3391165 | 0.81 | CTSD (0.49) | HPGDHTTRXFP1PRNPKDM4E | |
| SCHEMBL11326601 | 0.78 | RXFP1 (0.50) | HPGDRXFP1PRNPKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11464770-B2 | Anticancer pharmaceutical composition | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2022-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11464770-B2 | Anticancer pharmaceutical composition | MYC, MYCBP, TP53 | HPGD 3786/4885HTT 267/4885RXFP1 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.