SCHEMBL2098479

SCHEMBL2098479

c1ccc2nc(SSc3ccc4ccccc4n3)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 5/20 0.53
▸ PRNP P04156 5/20 0.53
▸ KDM4E B2RXH2 2/20 0.53
▸ ALDH1A1 P00352 5/20 0.50
▸ NPSR1 Q6W5P4 4/20 0.50
▸ NCF1 P14598 3/20 0.50
▸ CYP1A2 P05177 3/20 0.50
▸ MAPK10 P53779 2/20 0.50
▸ NOS2 P35228 1/20 0.50
▸ BACE1 P56817 1/20 0.50
▸ CA12 O43570 1/20 0.50
▸ CA9 Q16790 1/20 0.50
▸ RAB9A P51151 2/20 0.49
▸ HPGD P15428 3/20 0.47
▸ CYP3A4 P08684 2/20 0.47
▸ CYP2C9 P11712 2/20 0.47
▸ CYP2C19 P33261 2/20 0.47
▸ ALOX12 P18054 1/20 0.47
▸ HIF1A Q16665 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11326601 0.91 RXFP1 (0.50) RXFP1PRNPKDM4EALDH1A1NPSR1
Pyrimidine SCHEMBL6822462 0.88 RXFP1 (0.45) RXFP1PRNPKDM4EALDH1A1NPSR1
SCHEMBL7207052 0.86 EHMT2 (0.63) RXFP1PRNPKDM4EALDH1A1NPSR1
SCHEMBL6899659 0.85 RXFP1 (0.53) RXFP1PRNPKDM4EALDH1A1NPSR1
SCHEMBL29980222 0.82 HPGD (0.58) RXFP1PRNPKDM4EALDH1A1NPSR1
SCHEMBL2114821 0.82 HPGD (0.58) RXFP1PRNPKDM4EALDH1A1NPSR1
SCHEMBL2200585 0.81 NCF1 (0.52) RXFP1PRNPKDM4EALDH1A1NPSR1
SCHEMBL10411067 0.81 RXFP1 (0.50) RXFP1PRNPKDM4EALDH1A1NPSR1
SCHEMBL4370424 0.81 RXFP1 (0.50) RXFP1PRNPKDM4EALDH1A1NPSR1
SCHEMBL2817162 0.81 CYP1A2 (0.58) RXFP1PRNPKDM4EALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4314324-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS Ultima Genomics, Inc. (US) 2024-02-07 — — EP claimed
WO-2022212408-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS ULTIMA GENOMICS, INC. (US) 2022-10-06 — — WO claimed
US-6989263-B1 Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-01-24 — — US claimed
US-20030198648-A1 Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA ACHILION PHARMACEUTICALS 2003-10-23 — — US claimed
WO-2003060098-A2 METHODS FOR IDENTIFYING COMPOUNDS WHICH INHIBIT BINDING OF NUCLEOCAPSID 7 PROTEIN TO HIV-1 RNA ACHILLION PHARMACEUTICALS, INC. (US) 2003-07-24 — — WO claimed
EP-0782632-B1 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN US GOV HEALTH & HUMAN SERV (US) 2003-04-16 — — EP claimed
US-6001555-A DISSOCIATING A ZINC FINGER BY CONTACTING THE PROTEIN WITH A DISULFIDE, A MALEIMIDE, AN ALPHA-HALOGENATED KETONE, A HYDRAZIDE, A NITRIC OXIDE OR DERIVATIVES, CUPRIC IONS, FERRIC IONS OR THEIR COMPLEXES; SYNERGISTIC EFFECTS WITH VIRICIDES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-14 — — US claimed
EP-0782632-A1 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the Secretary of the Department of Health and Human Services (US) 1997-07-09 — — EP claimed
WO-1996009406-A9 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN — 1996-05-23 — — WO claimed
WO-1996009406-A1 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-03-28 — — WO claimed
US-20240132955-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS ULTIMA GENOMICS, INC. 2024-04-25 — — US disclosed
US-11939691-B2 Tin or tin alloy electroplating bath, and electronic component having electrodeposit formed thereon using the plating bath ISHIHARA CHEMICAL CO., LTD. (JP) 2024-03-26 — — US disclosed
EP-4314324-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS Ultima Genomics, Inc. (US) 2024-02-07 — — EP disclosed
WO-2022212408-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS ULTIMA GENOMICS, INC. (US) 2022-10-06 — — WO disclosed
CN-104448700-B Resin combination 味之素株式会社 2019-01-22 — — CN disclosed
EP-0248932-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-01-09 — — EP disclosed
US-4754016-A Process for preparing polyamide with organic phosphine/organic disulfide mixture condensing agent ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-06-28 — — US disclosed
US-4378364-A DITHIOBIS(PYRIDINE-CARBOXYLIC ACID) TO RELIEVE PAIN, INCREASE APPETITE GRASSETTI DAVIDE R 1983-03-29 — — US disclosed
US-4303765-A PEPTIZATION WITH AROMATIC POLYSULFIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-12-01 — — US disclosed
US-3937718-A CARBOXYLIC ACIDS, ALCOHOLS, TERTIERY PHOSPHINES, DISULFIDES, SULFENIC ACID ESTER SANKYO COMPANY LIMITED (JA) 1976-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030198648-A1 Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA MRPS27, SNRPE, NSUN2 RXFP1 4374/4885PRNP 626/4885KDM4E 4292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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