Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19553545 | 1.00 | ACHE (0.55) | ACHEHDAC4HDAC2HDAC8USP2 | |
| SCHEMBL15822170 | 0.84 | ACHE (0.62) | ACHEHDAC4HDAC2HDAC8ALDH1A1 | |
| SCHEMBL6056909 | 0.74 | HDAC4 (0.42) | HDAC4HDAC2HDAC8USP2ALDH1A1 | |
| SCHEMBL19553584 | 0.74 | ACHE (0.62) | ACHEALDH1A1METAP1 | |
| SCHEMBL19553658 | 0.74 | ACHE (0.57) | ACHEMETAP1 | |
| SCHEMBL29979613 | 0.74 | ACHE (0.57) | ACHEMETAP1 | |
| SCHEMBL22553427 | 0.74 | ACHE (0.57) | ACHEMETAP1 | |
| SCHEMBL22553468 | 0.74 | ACHE (0.57) | ACHEMETAP1 | |
| SCHEMBL29980503 | 0.74 | ACHE (0.57) | ACHEMETAP1 | |
| SCHEMBL29979392 | 0.74 | ACHE (0.57) | ACHEMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563438-B | Organic compounds | 奇华顿股份有限公司 | 2022-11-04 | — | — | CN | disclosed |