Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889560 | 0.89 | ALDH1A1 (0.46) | HDAC4HDAC2HDAC8HPGDHSD17B10 | |
| SCHEMBL4898011 | 0.82 | HSD17B10 (0.46) | HDAC4HDAC2HDAC8HPGDHSD17B10 | |
| SCHEMBL28964213 | 0.78 | CYP17A1 (0.52) | HDAC4HDAC2HDAC8HPGDHSD17B10 | |
| SCHEMBL15458064 | 0.77 | HSD17B10 (0.42) | HDAC4HDAC2HDAC8HPGDHSD17B10 | |
| SCHEMBL526598 | 0.77 | NPC1 (0.56) | HDAC4HDAC2HDAC8HPGDHSD17B10 | |
| SCHEMBL10064128 | 0.76 | MAOA (0.44) | HDAC4HDAC2HDAC8ALDH1A1GAA | |
| SCHEMBL8166417 | 0.76 | CLK4 (0.46) | HDAC4HDAC2HDAC8HPGDHSD17B10 | |
| SCHEMBL14269726 | 0.75 | MAOA (0.60) | HPGDHSD17B10ALDH1A1MAOAGFER | |
| SCHEMBL19553545 | 0.74 | ACHE (0.55) | HDAC4HDAC2HDAC8HPGDHSD17B10 | |
| SCHEMBL29980268 | 0.74 | ACHE (0.55) | HDAC4HDAC2HDAC8HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433211-B1 | SUBSTITUTED PENTACENE SEMICONDUCTORS | 3M INNOVATIVE PROPERTIES CO (US) | 2006-06-21 | — | — | EP | disclosed |
| US-20050288522-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2005-12-29 | — | — | US | disclosed |
| US-6974877-B2 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-12-13 | — | — | US | disclosed |
| US-6864396-B2 | Comprise at least one substituent selected from electron-donating substituents, halogen substituents, and combinations thereof; organic thin-film transistors | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-03-08 | — | — | US | disclosed |
| EP-1433211-A2 | SUBSTITUTED PENTACENE SEMICONDUCTORS | 3M Innovative Properties Company (US) | 2004-06-30 | — | — | EP | disclosed |
| EP-1430008-A2 | PROCESS FOR PREPARING PENTACENE DERIVATIVES | 3M Innovative Properties Company (US) | 2004-06-23 | — | — | EP | disclosed |
| US-20030105365-A1 | Comprise at least one substituent selected from electron-donating substituents, halogen substituents, and combinations thereof; organic thin-film transistors | 3M INNOVATIVE PROPERTIES COMPANY | 2003-06-05 | — | — | US | disclosed |
| US-20030100779-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-29 | — | — | US | disclosed |
| US-20030097010-A1 | Process for preparing pentacene derivatives | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-22 | — | — | US | disclosed |
| WO-2003028125-A2 | SUBSTITUTED PENTACENE SEMICONDUCTORS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2003027050-A2 | PROCESS FOR PREPARING PENTACENE DERIVATIVES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288522-A1 | Process for preparing pentacene derivatives | RARA, RARB, C9 | HDAC4 3476/4885HDAC2 2359/4885HDAC8 2678/4885 |
| US-20030097010-A1 | Process for preparing pentacene derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PCBP1, RARA | HDAC4 2932/4885HDAC2 1597/4885HDAC8 607/4885 |
| US-20030105365-A1 | Comprise at least one substituent selected from electron-donating substituents, halogen substituents, and combinations thereof; organic thin-film transistors | ETV1, HTR3C, SLC43A1 | HDAC4 2588/4885HDAC2 1677/4885HDAC8 2309/4885 |
| US-20030100779-A1 | Process for preparing pentacene derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PCBP1, RARA | HDAC4 2932/4885HDAC2 1597/4885HDAC8 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.