SCHEMBL299841

SCHEMBL299841

O=C1c2cccc3cccc(c23)C(=O)N1c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.71
KDM4E B2RXH2 4/20 0.71
SMN1; SMN2 Q16637 2/20 0.71
HPGD P15428 1/20 0.71
CA12 O43570 2/20 0.70
CA9 Q16790 2/20 0.70
L3MBTL1 Q9Y468 2/20 0.70
RXFP1 Q9HBX9 1/20 0.70
MAPT P10636 2/20 0.65
HTT P42858 2/20 0.65
GAA P10253 2/20 0.65
MAPK1 P28482 1/20 0.65
HSD17B10 Q99714 1/20 0.65
PDE6D O43924 1/20 0.63
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
KMT2A Q03164 4/20 0.60
USP2 O75604 2/20 0.60
KEAP1 Q14145 1/20 0.60
NFE2L2 Q16236 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20735193 0.92 ALDH1A1 (0.82) ALDH1A1KDM4ESMN1; SMN2HPGDCA12
SCHEMBL20210861 0.88 ALDH1A1 (0.57) ALDH1A1KDM4ESMN1; SMN2HPGDCA12
SCHEMBL9290287 0.87 PDE6D (0.82) ALDH1A1KDM4ESMN1; SMN2HPGDCA12
SCHEMBL20735204 0.86 ALDH1A1 (0.74) ALDH1A1KDM4ESMN1; SMN2HPGDCA12
SCHEMBL20735205 0.86 ALDH1A1 (0.74) ALDH1A1KDM4ESMN1; SMN2HPGDCA12
SCHEMBL28868331 0.86 ALDH1A1 (0.64) ALDH1A1KDM4ESMN1; SMN2HPGDCA12
SCHEMBL28839593 0.85 ALDH1A1 (0.62) ALDH1A1KDM4ESMN1; SMN2HPGDCA12
SCHEMBL22600682 0.84 KMT2A (0.71) ALDH1A1KDM4ESMN1; SMN2HPGDCA12
SCHEMBL9693019 0.84 ESR1 (0.58) ALDH1A1KDM4ESMN1; SMN2HPGDCA12
SCHEMBL25335143 0.83 ALDH1A1 (0.70) ALDH1A1KDM4ESMN1; SMN2HPGDCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850234-B N-phenyl-1, 8-naphthalimide derivative and preparation method and application thereof 厦门大学 2024-10-22 CN claimed
CN-115850234-A N-phenyl-1, 8-naphthalimide derivative and preparation method and application thereof 厦门大学 2023-03-28 CN claimed
CN-115850234-B N-phenyl-1, 8-naphthalimide derivative and preparation method and application thereof 厦门大学 2024-10-22 CN disclosed
CN-115850234-B N-phenyl-1, 8-naphthalimide derivative and preparation method and application thereof 厦门大学 2024-10-22 CN disclosed
CN-115850234-B N-phenyl-1, 8-naphthalimide derivative and preparation method and application thereof 厦门大学 2024-10-22 CN disclosed
CN-116332848-A Resonance energy transfer type red light aggregation-induced emission molecule and preparation method and application thereof 上海工程技术大学 2023-06-27 CN disclosed
CN-116332848-A Resonance energy transfer type red light aggregation-induced emission molecule and preparation method and application thereof 上海工程技术大学 2023-06-27 CN disclosed
CN-115850234-A N-phenyl-1, 8-naphthalimide derivative and preparation method and application thereof 厦门大学 2023-03-28 CN disclosed
CN-115850234-A N-phenyl-1, 8-naphthalimide derivative and preparation method and application thereof 厦门大学 2023-03-28 CN disclosed
CN-115850234-A N-phenyl-1, 8-naphthalimide derivative and preparation method and application thereof 厦门大学 2023-03-28 CN disclosed
CN-111533692-B Fluorescent molecular probe for detecting mercury ions and preparation method and application thereof 新疆农业大学 2021-11-16 CN disclosed
US-7393956-B2 Method for the production of perylen-3,4:9,10-tetracarboxylic acid diimides and perylen-3,4:9,10-tetracarboxylic acid dianhydride and naphtalene-1,8-dicarboxylimides BASF AKTIENGESELLSCHAFT (DE) 2008-07-01 US disclosed
US-20070110672-A1 SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors CERCACOR LABORATORIES, INC. 2007-05-17 US disclosed
CN-1902546-A Antireflective coatings for via filling and photolithography and methods of making the same HONEYWELL INT INC (US) 2007-01-24 CN disclosed
WO-2005097753-A1 METHOD FOR PRODUCING PERYLENE TETRACARBOXYLIC DIIMIDE DERIVATIVES UNIVERSITE DE PROVENCE AIX-MARSEILLE 1 (FR) 2005-10-20 WO disclosed
WO-2005065241-A2 SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS ARGOSE, INC. (US) 2005-07-21 WO disclosed
US-20050131220-A1 Method for the production of perylen-3,4:9,10-tetracarboxylic acid diimides and perylen-3,4:9,10-tetracarboxylic acid dianhydride and naphtalene-1,8-dicarboxylimides BASF AKTIENGESELLSCHAFT (DE) 2005-06-16 US disclosed
EP-1501897-A1 METHOD FOR THE PRODUCTION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIIMIDES AND PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIANHYDRIDE AND NAPHTALENE-1,8-DICARBOXYLIMIDES BASF AKTIENGESELLSCHAFT (DE) 2005-02-02 EP disclosed
WO-2003091345-A1 METHOD FOR THE PRODUCTION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIIMIDES AND PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIANHYDRIDE AND NAPHTALENE-1,8-DICARBOXYLIMIDES BASF AKTIENGESELLSCHAFT (DE) 2003-11-06 WO disclosed
US-5409780-A 3-oxy-N-(functionalized alkyl) anilines covalently bonded to bibulous strips through functional groups; quantitative analysis, accuracy CHEMTRAK, INC. (US) 1995-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050131220-A1 Method for the production of perylen-3,4:9,10-tetracarboxylic acid diimides and perylen-3,4:9,10-tetracarboxylic acid dianhydride and naphtalene-1,8-dicarboxylimides CBR1, CBR3, SCO2 ALDH1A1 2188/4885KDM4E 4636/4885SMN1; SMN2 2246/4885
US-20070110672-A1 SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors GCKR, SYMPK, SUCNR1 ALDH1A1 4364/4885KDM4E 2343/4885SMN1; SMN2 1311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.