SCHEMBL299850

SCHEMBL299850

O=C1OC(=O)Oc2cccc3cccc(c23)O1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 5/20 0.59
KDM4E B2RXH2 4/20 0.48
MAPK1 P28482 2/20 0.48
ATM Q13315 2/20 0.48
ALDH1A1 P00352 6/20 0.41
CES2 O00748 1/20 0.41
BCHE P06276 1/20 0.41
CES1 P23141 1/20 0.41
MCL1 Q07820 1/20 0.41
HSD17B10 Q99714 4/20 0.39
HPGD P15428 3/20 0.39
CYP3A4 P08684 2/20 0.39
CYP1A2 P05177 2/20 0.39
TSHR P16473 2/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
PARP1 P09874 1/20 0.37
PABPC1 P11940 1/20 0.35
DNMT1 P26358 1/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27705122 0.82 MAPK1 (0.65) TYMSKDM4EMAPK1ATMALDH1A1
SCHEMBL2591498 0.80 TYMS (0.44) TYMSKDM4EMAPK1ATMALDH1A1
SCHEMBL2588631 0.78 TYMS (0.50) TYMSKDM4EMAPK1ATMALDH1A1
SCHEMBL14627984 0.77 TYMS (0.80) TYMSKDM4EMAPK1ATMALDH1A1
SCHEMBL9055172 0.77 TYMS (0.38) TYMSTSHRALOX15
SCHEMBL29417603 0.77 MAPK1 (0.67) TYMSKDM4EMAPK1ATMALDH1A1
SCHEMBL5285168 0.76 ALOX15 (0.43) TYMSTSHRALOX15
SCHEMBL5669943 0.76 TYMS (0.36) TYMSALOX15
SCHEMBL4667769 0.76 TSHR (0.44) TYMSKDM4EALDH1A1TSHRPABPC1
SCHEMBL16612349 0.76 TYMS (0.39) TYMSKDM4EMAPK1ATMHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3049478-B1 A CURABLE EPOXY RESIN COMPOSITION BLUE CUBE IP LLC (US) 2018-08-01 EP claimed
EP-2864418-B1 INSULATING COMPOSITES FOR POWER TRANSMISSION AND DISTRIBUTION DOW GLOBAL TECHNOLOGIES LLC (US) 2017-08-16 EP claimed
EP-2421907-B1 THERMOSETTABLE COMPOSITION CONTAINING A HALF ESTER OF A CYCLOALIPHATIC DIOL AND A THERMOSET PRODUCT THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2016-11-23 EP claimed
EP-1501897-B1 METHOD FOR THE PRODUCTION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIIMIDES AND PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIANHYDRIDE AND NAPHTALENE-1,8-DICARBOXYLIMIDES BASF SE (DE) 2012-03-14 EP claimed
EP-1392422-B1 COATED GRANULAR MATERIAL AND METHOD FOR PRODUCTION THEREOF ASHLAND SUEDCHEMIE KERNFEST (DE) 2011-03-23 EP claimed
EP-1948736-B1 PROCESS FOR PREPARING FLAKE-FORM PARTICLES BASF SE (DE) 2011-03-16 EP claimed
EP-1945830-A1 CARRIER WITH POROUS VACUUM COATING Weinert, Hilmar (DE) 2008-07-23 EP claimed
WO-2007054229-A1 CARRIER WITH POROUS VACUUM COATING WEINERT HILMAR (DE) 2007-05-18 WO claimed
EP-1118644-B1 Hot melt printing ink SIEGWERK DRUCKFARBEN AG (DE) 2006-06-14 EP claimed
EP-1404763-B1 METHOD FOR THE PRODUCTION OF PLANE-PARALLEL PLATELETS BY USING ORGANIC SEPARATING AGENTS CIBA SC HOLDING AG (CH) 2005-10-05 EP claimed
EP-1501897-A1 METHOD FOR THE PRODUCTION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIIMIDES AND PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIANHYDRIDE AND NAPHTALENE-1,8-DICARBOXYLIMIDES BASF AKTIENGESELLSCHAFT (DE) 2005-02-02 EP claimed
WO-2003091345-A1 METHOD FOR THE PRODUCTION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIIMIDES AND PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIANHYDRIDE AND NAPHTALENE-1,8-DICARBOXYLIMIDES BASF AKTIENGESELLSCHAFT (DE) 2003-11-06 WO claimed
EP-1206456-A1 THERMOCHROMIC RYLENE DYES BASF AKTIENGESELLSCHAFT (DE) 2002-05-22 EP claimed
EP-1118644-A2 Hot melt printing ink Siegwerk Druckfarben GmbH & Co. KG (DE) 2001-07-25 EP claimed
WO-2001016109-A1 THERMOCHROMIC RYLENE DYES BASF AKTIENGESELLSCHAFT (DE) 2001-03-08 WO claimed
EP-0523240-B1 BISIMIDE COMPOUNDS, POLYIMIDE RESIN COMPOSITION PREPARED THEREFROM, AND CARBON FIBER-REINFORCED POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1996-03-20 EP claimed
EP-3548534-B1 METHOD FOR THE PREPARATION OF TDI-BASED POLYURETHANE FOAMS CONTAINING ORGANIC ACID ANHYDRIDES AND/OR ORGANIC ACID CHLORIDES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2020-12-02 EP disclosed
EP-3330308-A1 METHOD FOR THE PREPARATION OF TDI-BASED POLYURETHANE FOAMS CONTAINING ORGANIC ACID ANHYDRIDES AND/OR ORGANIC ACID CHLORIDES Covestro Deutschland AG (DE) 2018-06-06 EP disclosed
EP-0295488-A2 Process for the preparation of 1,8-naphthalimides BAYER AG (DE) 1988-12-21 EP disclosed
EP-0152819-A1 Light-sensitive mixture with diazoresins and light-sensitive registration material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1985-08-28 EP disclosed