Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NGFR | P08138 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272402 | 0.87 | CYP19A1 (0.39) | TSHRTDP1MEN1KMT2ALMNA | |
| SCHEMBL299850 | 0.76 | TYMS (0.59) | TSHRMEN1KMT2APABPC1POLB | |
| SCHEMBL10788183 | 0.73 | TSHR (0.58) | TSHRTDP1MEN1KMT2AFTO | |
| SCHEMBL29903867 | 0.73 | TSHR (0.58) | TSHRTDP1MEN1KMT2AFTO | |
| SCHEMBL1565380 | 0.72 | TYMS (0.61) | TDP1MEN1KMT2AFTOPABPC1 | |
| SCHEMBL29532369 | 0.72 | TYMS (0.61) | TDP1MEN1KMT2AFTOPABPC1 | |
| SCHEMBL4666425 | 0.69 | ALDH1A1 (0.49) | TDP1MEN1KMT2APABPC1LMNA | |
| SCHEMBL1826053 | 0.68 | TDP1 (0.62) | TSHRTDP1MEN1KMT2ALMNA | |
| SCHEMBL30738237 | 0.68 | TDP1 (0.62) | TSHRTDP1MEN1KMT2AFTO | |
| SCHEMBL30503606 | 0.68 | TDP1 (0.62) | TSHRTDP1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1729723-B1 | NEUTRAL AND CATIONIC NAPHTHALENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS FOR DYEING KERATIN FIBERS | WELLA AG (DE) | 2008-06-04 | — | — | EP | disclosed |
| EP-1729723-A1 | NEUTRAL AND CATIONIC NAPHTHALENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS FOR DYEING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2006-12-13 | — | — | EP | disclosed |
| EP-1720513-A1 | LIGHTENING DIRECT DYESTUFFS FOR KERATIN FIBERS AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005074872-A1 | LIGHTENING DIRECT DYESTUFFS FOR KERATIN FIBERS AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |
| WO-2005075574-A1 | NEUTRAL AND CATIONIC NAPHTHALENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS FOR DYEING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |