Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.35 |
| ▸ | GLA | P06280 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.35 |
| ▸ | CASP1 | P29466 | 5/20 | 0.35 |
| ▸ | CASP7 | P55210 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 8/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993404 | 0.79 | MAPK8 (0.40) | CDK4CDK2MAT2AARACACB | |
| SCHEMBL30850669 | 0.77 | CDK4 (0.35) | CDK4CDK2MAT2AP2RX3P2RX2 | |
| SCHEMBL29985144 | 0.73 | MEN1 (0.33) | ALDH1A1HSD17B10GLACYP1A2CYP2C19 | |
| SCHEMBL6357736 | 0.71 | CXCR2 (0.42) | CDK4CDK2P2RX3P2RX2MAPK1 | |
| SCHEMBL16266657 | 0.68 | LRRK2 (0.40) | CDK4CDK2MAT2AP2RX3P2RX2 | |
| SCHEMBL6493178 | 0.68 | CDK4 (0.38) | CDK4CDK2 | |
| SCHEMBL30141680 | 0.65 | MAT2A (0.37) | ALDH1A1HSD17B10GLACYP1A2CASP1 | |
| SCHEMBL5612934 | 0.64 | CYP1A2 (0.47) | ALDH1A1HSD17B10GLACYP1A2CASP1 | |
| SCHEMBL19552131 | 0.63 | NPC1 (0.42) | CDK4CDK2MAT2AP2RX3P2RX2 | |
| SCHEMBL16993046 | 0.63 | MAPK8 (0.44) | CDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206730-A1 | PYRIMIDOPYRAZINE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-10-06 | — | — | WO | disclosed |