Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 3/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141680 | 0.80 | MAT2A (0.37) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL4573075 | 0.76 | CYP1A2 (0.47) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL7508716 | 0.76 | ALDH1A1 (0.37) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL29985137 | 0.73 | CDK4 (0.36) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL25272619 | 0.67 | TYRO3 (0.50) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL21428809 | 0.65 | MEN1 (0.39) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL5612934 | 0.64 | CYP1A2 (0.47) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL30808338 | 0.64 | LMNA (0.42) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL25163414 | 0.63 | RXRA (0.43) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL17240893 | 0.63 | MKNK1 (0.36) | MEN1KMT2ACYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206730-A1 | PYRIMIDOPYRAZINE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-10-06 | — | — | WO | disclosed |