Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335852 | 0.98 | HPGD (0.51) | KCNA3HPGDPKMNPC1EPHX2 | |
| Ethylene SCHEMBL27549601 | 0.96 | HPGD (0.47) | KCNA3HPGDPKMNPC1EPHX2 | |
| SCHEMBL321228 | 0.87 | FOXM1 (0.63) | HPGDNPC1RAB9ASMN1; SMN2FOXM1 | |
| SCHEMBL320195 | 0.81 | ADRB2 (0.52) | HPGDADRB2ADRB1ADRB3 | |
| SCHEMBL321332 | 0.81 | HPGD (0.47) | HPGDSMN1; SMN2ADRB2ADRB1ADRB3 | |
| SCHEMBL24415464 | 0.81 | KCNA3 (0.42) | KCNA3HPGDPKMNPC1EPHX2 | |
| SCHEMBL5514779 | 0.81 | ALDH1A1 (0.47) | KCNA3PKMNPC1EPHX2RAB9A | |
| SCHEMBL5521307 | 0.81 | TAAR1 (0.47) | KCNA3PKMADRB2ADRB1ADRB3 | |
| SCHEMBL5521304 | 0.81 | TAAR1 (0.47) | KCNA3PKMADRB2ADRB1ADRB3 | |
| SCHEMBL5514782 | 0.81 | ALDH1A1 (0.47) | KCNA3PKMNPC1EPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304502-B | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-10-18 | — | — | CN | disclosed |
| CN-115304502-A | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-08 | — | — | CN | disclosed |