Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.42 |
| ▸ | DPP4 | P27487 | 5/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814439 | 1.00 | NAMPT (0.46) | NAMPTDPP9DPP4DPP8DPP7 | |
| SCHEMBL29987597 | 0.78 | HSD17B10 (0.54) | NAMPTROCK2NPC1ALDH1A1HPGD | |
| SCHEMBL24814730 | 0.78 | HSD17B10 (0.54) | NAMPTROCK2NPC1ALDH1A1HPGD | |
| SCHEMBL29986739 | 0.77 | NAMPT (0.44) | NAMPTDPP9DPP4DPP8DPP7 | |
| SCHEMBL24814397 | 0.77 | NAMPT (0.44) | NAMPTDPP9DPP4DPP8DPP7 | |
| SCHEMBL24814438 | 0.76 | ALDH1A1 (0.50) | NAMPTDPP9HSP90B1TRAP1ROCK2 | |
| SCHEMBL29987272 | 0.76 | ALDH1A1 (0.50) | NAMPTDPP9HSP90B1TRAP1ROCK2 | |
| SCHEMBL24814735 | 0.72 | DPP9 (0.55) | DPP9DPP4DPP8DPP7HSP90B1 | |
| SCHEMBL29986254 | 0.72 | DPP9 (0.55) | DPP9DPP4DPP8DPP7HSP90B1 | |
| SCHEMBL24814388 | 0.71 | ALDH1A1 (0.44) | NAMPTNPC1ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |