Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.42 |
| ▸ | DPP4 | P27487 | 6/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814397 | 1.00 | NAMPT (0.44) | NAMPTDPP9DPP4DPP8DPP7 | |
| SCHEMBL29987274 | 0.79 | NAMPT (0.46) | NAMPTDPP9DPP4DPP8DPP7 | |
| SCHEMBL24814393 | 0.79 | NAMPT (0.46) | NAMPTDPP9DPP4DPP8DPP7 | |
| SCHEMBL24815720 | 0.77 | NAMPT (0.45) | NAMPTDPP9DPP4DPP8DPP7 | |
| SCHEMBL24814439 | 0.77 | NAMPT (0.46) | NAMPTDPP9DPP4DPP8DPP7 | |
| SCHEMBL29986479 | 0.77 | NAMPT (0.46) | NAMPTDPP9DPP4DPP8DPP7 | |
| SCHEMBL29986254 | 0.72 | DPP9 (0.55) | DPP9DPP4DPP8DPP7HSP90B1 | |
| SCHEMBL24814735 | 0.72 | DPP9 (0.55) | DPP9DPP4DPP8DPP7HSP90B1 | |
| SCHEMBL24815722 | 0.70 | SMN1; SMN2 (0.38) | NAMPTGAALMNA | |
| SCHEMBL8401777 | 0.70 | DPP9 (0.62) | NAMPTDPP9DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |