Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.40 |
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814393 | 1.00 | NAMPT (0.46) | NAMPTROCK2ROCK1DPP9HSP90B1 | |
| SCHEMBL24815720 | 0.89 | NAMPT (0.45) | NAMPTROCK2ROCK1DPP9HSP90B1 | |
| SCHEMBL29986504 | 0.88 | ALDH1A1 (0.44) | NAMPT | |
| SCHEMBL24815671 | 0.88 | ALDH1A1 (0.44) | NAMPT | |
| SCHEMBL24815700 | 0.87 | ESR1 (0.40) | NAMPT | |
| SCHEMBL29986903 | 0.87 | ESR1 (0.40) | NAMPT | |
| SCHEMBL26845914 | 0.86 | NAMPT (0.43) | NAMPTDPP9DPP8DPP7 | |
| SCHEMBL29987244 | 0.84 | NAMPT (0.46) | NAMPTROCK1 | |
| SCHEMBL24815715 | 0.84 | NAMPT (0.46) | NAMPTROCK1 | |
| SCHEMBL24814430 | 0.82 | SMN1; SMN2 (0.55) | NAMPTROCK2ROCK1DPP9HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |