Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24816151 | 1.00 | ATM (0.64) | ATMALDH1A1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL29987226 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAPTSMN1; SMN2NPC1GAA | |
| SCHEMBL24814437 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAPTSMN1; SMN2NPC1GAA | |
| SCHEMBL18719836 | 0.79 | ATM (0.97) | ATMALDH1A1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL14970858 | 0.78 | ALDH1A1 (0.69) | ATMALDH1A1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL17175792 | 0.77 | GAA (0.68) | ALDH1A1HSD17B10MAPTSMN1; SMN2NPC1 | |
| SCHEMBL24815794 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HSD17B10MAPTSMN1; SMN2NPC1 | |
| SCHEMBL24814748 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MAPTSMN1; SMN2NPC1 | |
| SCHEMBL29986865 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MAPTSMN1; SMN2NPC1 | |
| SCHEMBL29986787 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HSD17B10MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |