Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814437 | 1.00 | ALDH1A1 (0.65) | ALDH1A1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL24816151 | 0.84 | ATM (0.64) | ALDH1A1MAPTGAASMN1; SMN2PKM | |
| SCHEMBL29986879 | 0.84 | ATM (0.64) | ALDH1A1MAPTGAASMN1; SMN2PKM | |
| SCHEMBL29986865 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL24814748 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL29986787 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL24815794 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL24814434 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL29986261 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL24815859 | 0.73 | RAB9A (0.61) | ALDH1A1MAPTSMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |