Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24815672 | 1.00 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2POLBNOTUMRAB9A | |
| SCHEMBL24815671 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBNOTUMRAB9A | |
| SCHEMBL29986504 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBNOTUMRAB9A | |
| SCHEMBL29987245 | 0.81 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2POLBNOTUMRAB9A | |
| SCHEMBL24816165 | 0.81 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2POLBNOTUMRAB9A | |
| SCHEMBL24815673 | 0.80 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2POLBNOTUMRAB9A | |
| SCHEMBL29986910 | 0.80 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2POLBNOTUMRAB9A | |
| SCHEMBL24815706 | 0.79 | NAMPT (0.42) | ALDH1A1SMN1; SMN2POLBNOTUMRAB9A | |
| SCHEMBL24815669 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2POLBNOTUMRAB9A | |
| SCHEMBL29986905 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2POLBNOTUMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |