Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24816165 | 1.00 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRMAPK1NAMPT | |
| SCHEMBL24815672 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRMAPK1NAMPT | |
| SCHEMBL29987155 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRMAPK1NAMPT | |
| SCHEMBL29986907 | 0.80 | GAA (0.47) | ALDH1A1LMNATSHRMAPK1NAMPT | |
| SCHEMBL24814425 | 0.80 | GAA (0.47) | ALDH1A1LMNATSHRMAPK1NAMPT | |
| SCHEMBL24815896 | 0.79 | GRM1 (0.37) | TSHRMAPK1POLBSMN1; SMN2 | |
| SCHEMBL29986504 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNANAMPTKDM4EHPGD | |
| SCHEMBL24815671 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNANAMPTKDM4EHPGD | |
| SCHEMBL24815703 | 0.74 | NAMPT (0.43) | ALDH1A1LMNATSHRMAPK1NAMPT | |
| SCHEMBL29986911 | 0.74 | NAMPT (0.43) | ALDH1A1LMNATSHRMAPK1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |