Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.74 |
| ▸ | FEN1 | P39748 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180621 | 0.90 | ERCC5 (0.68) | ERCC5FEN1RAB9AMEN1KMT2A | |
| SCHEMBL31582272 | 0.90 | MEN1 (0.69) | ERCC5FEN1RAB9AMEN1KMT2A | |
| SCHEMBL4020872 | 0.89 | ERCC5 (0.72) | ERCC5FEN1RAB9AMEN1KMT2A | |
| SCHEMBL29033943 | 0.89 | ERCC5 (0.67) | ERCC5FEN1RAB9AMEN1KMT2A | |
| SCHEMBL30802824 | 0.87 | ERCC5 (0.65) | ERCC5FEN1RAB9AMEN1KMT2A | |
| SCHEMBL2519308 | 0.87 | ERCC5 (0.65) | ERCC5FEN1RAB9AMEN1KMT2A | |
| SCHEMBL2492019 | 0.87 | ERCC5 (0.65) | ERCC5FEN1RAB9AMEN1KMT2A | |
| SCHEMBL15979733 | 0.86 | CES2 (0.62) | ERCC5FEN1RAB9AMEN1KMT2A | |
| SCHEMBL28066677 | 0.86 | FEN1 (1.00) | ERCC5FEN1RAB9AMEN1KMT2A | |
| SCHEMBL853580 | 0.84 | ERCC5 (0.61) | ERCC5FEN1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093323-B | Beta-functionalized chiral homoallylic alcohol derivative and preparation method and application thereof | 武汉大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-115093323-A | Beta-functionalized chiral homoallyl alcohol derivative and preparation method and application thereof | 武汉大学 | 2022-09-23 | — | — | CN | disclosed |