Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MGAT3 | Q09327 | 3/20 | 0.41 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24815715 | 1.00 | NAMPT (0.46) | NAMPTROCK1TAAR1STSESR1 | |
| SCHEMBL26845914 | 0.86 | NAMPT (0.43) | NAMPTTAAR1TSHRMEN1KMT2A | |
| SCHEMBL29986504 | 0.86 | ALDH1A1 (0.44) | NAMPTHPGDHSD17B10ALDH1A1 | |
| SCHEMBL24815671 | 0.86 | ALDH1A1 (0.44) | NAMPTHPGDHSD17B10ALDH1A1 | |
| SCHEMBL29986903 | 0.85 | ESR1 (0.40) | NAMPTESR1ESR2ALDH1A1CA1 | |
| SCHEMBL24815700 | 0.85 | ESR1 (0.40) | NAMPTESR1ESR2ALDH1A1CA1 | |
| SCHEMBL24814393 | 0.84 | NAMPT (0.46) | NAMPTROCK1 | |
| SCHEMBL29987274 | 0.84 | NAMPT (0.46) | NAMPTROCK1 | |
| SCHEMBL24814391 | 0.79 | RYR2 (0.43) | NAMPTROCK1TAAR1ESR1ESR2 | |
| SCHEMBL24814718 | 0.78 | AOC3 (0.49) | NAMPTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |