SCHEMBL29987259

SCHEMBL29987259

O=C(O)c1ccc2ncn(C[C@@H]3CCCO3)c2c1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.54
PTGER4 P35408 1/20 0.48
ALDH1A1 P00352 2/20 0.47
HCAR3 P49019 1/20 0.46
GRIN2B Q13224 1/20 0.46
CTSD P07339 2/20 0.45
TSHR P16473 2/20 0.44
HSD17B10 Q99714 1/20 0.44
GAA P10253 1/20 0.44
FGFR1 P11362 1/20 0.44
GLP1R P43220 3/20 0.44
HTT P42858 1/20 0.43
TBXA2R P21731 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558920 1.00 KDM4C (0.54) KDM4CPTGER4ALDH1A1HCAR3GRIN2B
SCHEMBL29159941 0.98 KDM4C (0.52) KDM4CPTGER4ALDH1A1HCAR3GRIN2B
SCHEMBL30020531 0.98 KDM4C (0.52) KDM4CPTGER4ALDH1A1HCAR3GRIN2B
SCHEMBL30548170 0.94 FGFR1 (0.47) KDM4CPTGER4GRIN2BHSD17B10GAA
SCHEMBL20268541 0.94 FGFR1 (0.47) KDM4CPTGER4GRIN2BHSD17B10GAA
SCHEMBL23361781 0.94 FGFR1 (0.47) KDM4CPTGER4GRIN2BHSD17B10GAA
SCHEMBL29393184 0.94 FGFR1 (0.47) KDM4CPTGER4GRIN2BHSD17B10GAA
Ammonia Solution, Strong SCHEMBL30676125 0.93 FGFR1 (0.46) KDM4CPTGER4GRIN2BHSD17B10GAA
Tromethamine SCHEMBL30922345 0.87 KDM4C (0.41) KDM4CPTGER4CTSDHSD17B10GAA
SCHEMBL29558894 0.87 ALDH1A1 (0.53) ALDH1A1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250236627-A1 CERTAIN OCTAHYDROFURO[3,4- B]PYRAZINES AS GLP-1 RECEPTOR MODULATORS ASTRAZENECA AB (SE) 2025-07-24 US disclosed
EP-4582421-A2 GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME LG Chem, Ltd. (KR) 2025-07-09 EP disclosed
CN-119923395-A N-heterocyclic GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof 卡莫特医疗有限公司 2025-05-02 CN disclosed
US-20240300928-A1 GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME LG CHEM, LTD. (KR) 2024-09-12 US disclosed
EP-4373821-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF Hepagene Therapeutics (HK) Limited (HK) 2024-05-29 EP disclosed
EP-4303215-A1 GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME Lg Chem, Ltd. (KR) 2024-01-10 EP disclosed
WO-2023001237-A1 GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF Hepagene Therapeutics (HK) Limited (CN) 2023-01-26 WO disclosed
WO-2022216094-A1 GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME 주식회사 엘지화학 2022-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240300928-A1 GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME GLP1R, GPR119, DMPK KDM4C 2145/4885PTGER4 2044/4885ALDH1A1 3793/4885
US-20250236627-A1 CERTAIN OCTAHYDROFURO[3,4- B]PYRAZINES AS GLP-1 RECEPTOR MODULATORS GLP1R, GIPR, GPR119 KDM4C 3266/4885PTGER4 348/4885ALDH1A1 746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.