Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.72 |
| ▸ | CES1 | P23141 | 3/20 | 0.65 |
| ▸ | CES2 | O00748 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29668521 | 0.94 | HPGD (0.71) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL28346776 | 0.94 | HPGD (0.71) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL4944399 | 0.90 | MEN1 (0.61) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL30114944 | 0.89 | HPGD (0.65) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL28972819 | 0.89 | HPGD (0.65) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL28972820 | 0.89 | HPGD (0.65) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL3022836 | 0.88 | MEN1 (0.59) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL3026885 | 0.88 | MEN1 (0.59) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL1924322 | 0.85 | PLOD2 (0.64) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL2056918 | 0.85 | MEN1 (0.56) | MEN1KMT2AHPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466817-A | Preparation method of polysubstituted pyrazole derivative | 华侨大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115093323-B | Beta-functionalized chiral homoallylic alcohol derivative and preparation method and application thereof | 武汉大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-115093323-A | Beta-functionalized chiral homoallyl alcohol derivative and preparation method and application thereof | 武汉大学 | 2022-09-23 | — | — | CN | disclosed |