Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315926 | 0.87 | CTNNB1 (0.54) | MEN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL1167035 | 0.85 | NPC1 (0.55) | MEN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL29987428 | 0.85 | MEN1 (0.72) | MEN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL20487359 | 0.83 | KDM4E (0.54) | MEN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL3022836 | 0.82 | MEN1 (0.59) | MEN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL3026885 | 0.82 | MEN1 (0.59) | MEN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL4457800 | 0.82 | CES2 (0.46) | MEN1KMT2AKDM4ENPC1LMNA | |
| SCHEMBL7671012 | 0.81 | KDM4E (0.53) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL1505243 | 0.81 | LOXL2 (0.56) | MEN1KMT2ANPC1HPGDTSHR | |
| SCHEMBL1398937 | 0.81 | CTNNB1 (0.56) | MEN1KMT2AKDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105112460-A | Method for producing (S)-4-methylbenzene methyl propionate from cells | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-12-02 | — | — | CN | claimed |
| US-6410757-B1 | TAXANE COMPOUNDS | BIO RESEARCH CORPORATION OF YOKOHAMA (JP) | 2002-06-25 | — | — | US | claimed |
| CN-105112460-A | Method for producing (S)-4-methylbenzene methyl propionate from cells | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-12-02 | — | — | CN | disclosed |
| US-20110105491-A1 | THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-05-05 | — | — | US | disclosed |
| WO-2010004507-A1 | THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-01-14 | — | — | WO | disclosed |
| EP-1029857-B1 | Baccatin derivatives and a process for producing the same | BIO RES CORP OF YOKOHAMA (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-6410757-B1 | TAXANE COMPOUNDS | BIO RESEARCH CORPORATION OF YOKOHAMA (JP) | 2002-06-25 | — | — | US | disclosed |
| JP-2000239267-A | BACCATINE DERIVATIVE AND ITS PRODUCTION | YOKOHAMA KOKUSAI BIO KENKYUSHO:KK | 2000-09-05 | — | — | JP | disclosed |
| EP-1029857-A1 | Baccatin derivatives and a process for producing the same | Bio Research Corporation of Yokohama (JP) | 2000-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105491-A1 | THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | HCRTR2, HCRTR1, OXTR | MEN1 659/4885KMT2A 1736/4885KDM4E 3641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.