Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814720 | 1.00 | RAB9A (0.65) | RAB9APOLBSMN1; SMN2NPC1KMT2A | |
| SCHEMBL24815673 | 0.84 | SMN1; SMN2 (0.67) | RAB9APOLBSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL29986910 | 0.84 | SMN1; SMN2 (0.67) | RAB9APOLBSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL24815801 | 0.80 | ALDH1A1 (0.48) | RAB9APOLBSMN1; SMN2NPC1KMT2A | |
| SCHEMBL29987207 | 0.80 | ALDH1A1 (0.48) | RAB9APOLBSMN1; SMN2NPC1KMT2A | |
| SCHEMBL29367172 | 0.77 | HDAC3 (0.63) | SMN1; SMN2KMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL28500343 | 0.76 | HDAC3 (0.66) | SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL24814459 | 0.76 | ALDH1A1 (0.46) | RAB9APOLBSMN1; SMN2NPC1KMT2A | |
| SCHEMBL24815692 | 0.76 | ALDH1A1 (0.44) | RAB9APOLBSMN1; SMN2NPC1KMT2A | |
| SCHEMBL29987376 | 0.76 | ALDH1A1 (0.44) | RAB9APOLBSMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |