Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | ADCY1 | Q08828 | 5/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29988165 | 0.91 | AKR1C3 (0.34) | PDK2NPC1RAB9AADCY1EPHX2 | |
| SCHEMBL408394 | 0.87 | NPC1 (0.42) | NPC1RAB9AADCY1EPHX2AKR1C3 | |
| SCHEMBL439761 | 0.87 | NPC1 (0.42) | NPC1RAB9AADCY1EPHX2AKR1C3 | |
| SCHEMBL29988139 | 0.82 | ADCY1 (0.36) | PDK2GRM5ADCY1EPHX2ADCY8 | |
| Trifluoroacetic Acid SCHEMBL29987840 | 0.81 | SMYD3 (0.35) | PDK2TBK1ADCY1EPHX2HDAC3 | |
| SCHEMBL671389 | 0.79 | LMNA (0.43) | NPC1RAB9AAKR1C3AKR1C1MEN1 | |
| SCHEMBL671388 | 0.79 | LMNA (0.43) | NPC1RAB9AAKR1C3AKR1C1MEN1 | |
| SCHEMBL1240344 | 0.79 | LMNA (0.43) | NPC1RAB9AAKR1C3AKR1C1MEN1 | |
| SCHEMBL408425 | 0.79 | TNKS (0.39) | NPC1RAB9AADCY1EPHX2AKR1C3 | |
| SCHEMBL440024 | 0.79 | TNKS (0.39) | NPC1RAB9AADCY1EPHX2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212902-A1 | MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY | ALTOS LABS, INC. (US) | 2022-10-06 | — | — | WO | disclosed |