Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.56 |
| ▸ | CTSK | P43235 | 14/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239753 | 0.87 | CTSS (0.72) | CTSSCTSKCAPN1CTSLCTSB | |
| SCHEMBL14611701 | 0.85 | CTSS (0.57) | CTSSCTSKCAPN1CTSLCTSB | |
| SCHEMBL9559452 | 0.84 | CTSS (0.54) | CTSSCTSKCTSLCTSB | |
| SCHEMBL9559449 | 0.84 | CTSS (0.54) | CTSSCTSKCTSLCTSB | |
| SCHEMBL28544565 | 0.84 | CTSS (0.50) | CTSSCTSKCAPN1CTSLCTSB | |
| SCHEMBL28544563 | 0.84 | CTSS (0.50) | CTSSCTSKCAPN1CTSLCTSB | |
| SCHEMBL31285591 | 0.84 | CYP1A2 (0.53) | CTSSCTSKCAPN1CTSLCTSB | |
| SCHEMBL14145896 | 0.83 | CTSK (0.48) | CTSSCTSKCTSLCTSBCYP1A2 | |
| SCHEMBL14984665 | 0.83 | CTSK (0.48) | CTSSCTSKCTSLCTSBCYP1A2 | |
| SCHEMBL1564513 | 0.83 | KDM4E (0.55) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197749-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197749-A1 | CHEMICAL COMPOUNDS | EDF1, ECE1, EDNRA | CTSS 2930/4885CTSK 3115/4885CAPN1 3243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.