Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.36 |
| ▸ | GSK3A | P49840 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29989192 | 0.80 | GSK3B (0.40) | GSK3BGSK3AMAPTFLT3MAP3K5 | |
| SCHEMBL23612065 | 0.80 | GSK3B (0.40) | GSK3BGSK3AMAPTFLT3MAP3K5 | |
| SCHEMBL29988619 | 0.74 | CNR2 (0.36) | GSK3BGSK3ASCN10A | |
| SCHEMBL30021808 | 0.71 | GSK3B (0.46) | GSK3BGSK3AMAPTSCN10A | |
| SCHEMBL23611983 | 0.71 | GSK3B (0.46) | GSK3BGSK3AMAPTSCN10A | |
| SCHEMBL30020868 | 0.70 | GSK3B (0.36) | GSK3BGSK3AMAPTFLT3SCN10A | |
| SCHEMBL23612055 | 0.69 | GSK3B (0.47) | GSK3BGSK3AMAPTFLT3SCN10A | |
| SCHEMBL30089458 | 0.69 | TRPC6 (0.45) | — | |
| SCHEMBL23623101 | 0.68 | GSK3B (0.46) | GSK3BGSK3AMAPTKIF18A | |
| SCHEMBL29988590 | 0.68 | GSK3B (0.46) | GSK3BGSK3AMAPTKIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4085051-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2022-11-09 | — | — | EP | disclosed |
| EP-4085061-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2022-11-09 | — | — | EP | disclosed |